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Understanding Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a relentless neurodegenerative disorder that targets the motor neurons—the nerve cells responsible for controlling voluntary muscle movement. While it is a devastating diagnosis, understanding the mechanics of the disease is the first step in navigating the journey for patients and their families.

The Pathophysiology of ALS

In a healthy body, motor neurons in the brain (upper motor neurons) send signals to motor neurons in the spinal cord (lower motor neurons), which then tell the muscles to move. In ALS, these neurons gradually deteriorate and die.


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